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Studying Factors contributing to muscle loss or strength

Developing an invitro system of human skeletal muscle to validate biomarkers of sarcopenia. - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/01/101280
Enrollment
12
Registered
2026-01-15
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M233- Other meniscus derangements

Interventions

Intervention1: nil: nil Intervention2: Nil: Nil Intervention3: Nil: Nil Control Intervention1: nil: nil

Sponsors

inStem
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Apparently healthy young adults (20-40 years) undergoing arthroscopic knee surgeries 2. People above 60 undergoing arthroscopic knee surgeries/total knee replacement surgeries

Exclusion criteria

Exclusion criteria: 1. End organ failure 2. Malignancy 3. Psychiatric disorders/poor mental health

Design outcomes

Secondary

MeasureTime frame
To validate the invitro system of human myoblast by comparing biomarkers and signatures of sarcopenic and non sarcopenic muscle fibresTimepoint: 6 months;To test the effect of metabolic factors (including a few amino acids and a dietary flavanone) on skeletal muscle myogenesis and metabolism as surrogate measurements for sarcopenia in the invitro system developed. of human myoblastTimepoint: 6 months—

Primary

MeasureTime frame
To develop an an invitro system of human myoblast (Isolation and culture of human primary muscle progenitor cells (hMPCs))Timepoint: 6 months—

Countries

India

Contacts

Public ContactDr Niranjan

Bangalore Baptist Hospital

onsnir@yahoo.co.in9449001918

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026