Effectiveness of Two Bone-Regrowth Materials on Bone Height and strength Following Dental Implant Surgery

Comparative Evaluation of Effectiveness of Recombinant Human Bone Morphogenetic Protein-2 and Titanium Platelet Rich Fibrin on Crestal Bone Height and Bone Density After Implant Placement: A Randomized Controlled Clinical Trial. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/101216

Enrollment

Registered

2026-01-15

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: recombinant human bone morphogenetic protein 2: a growth factor produced by recombinant DNA technology Intervention2: titanium platelet rich fibrin: autologous platelet concentrate rich

Eligibility

Inclusion criteria

Inclusion criteria: Subjects free of any systemic diseases that may affect bone quality. Subjects having sufficient interarch space, bone thickness and height, normal maxilla-mandibular relationship, and the absence of TMJ pathosis.

Exclusion criteria

Exclusion criteria: Subjects with any systemic disorders such as cardiovascular disease, diabetes mellitus, thyroid and parathyroid abnormalities. Subjects currently on antibiotics, steroids, or hormonal therapy. Pregnant women and lactating mothers. Smokers & tobacco chewers.

Design outcomes

Primary

Measure	Time frame
Crestal bone height Bone density Width of keratinized mucosaTimepoint: immediate, 1 month, 3 months	—

Secondary

Measure	Time frame
NIL Timepoint: NIL	—

Countries

India

Contacts

Public ContactDr Kanika Singhal

Department of Periodontology, Government Dental College and Hospital, RUHS-CDS, Jaipur, 302016

sharmisthavijay@yahoo.com9414045444

Outcome results