Comparison between the efficacy of two types of interventions External oblique rectus abdominis and Subcostal transverse abdominis plane block in pain relief in patients undergoing laparoscopic cholecystectomy

Comparison of External Oblique and Rectus Abdominis Plane (EXORA) block with Subcostal Transverse Abdominis Plane (TAP) Block for post operative Analgesia in Laparoscopic Cholecystectomy - nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/101200

Enrollment

Registered

2026-01-15

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis Health Condition 2: K800- Calculus of gallbladder with acutecholecystitis Health Condition 3: K00-K95- Diseases of the digestive system

Interventions

Intervention1: Ultrasound Guided External Oblique And Rectus Abdominis Plane (EXORA) Block. 0.25% Bupivacaine injection : Comparison of External Oblique and Rectus Abdominis Plane (EXORA) Block with S

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18 to 65 years- ASA physical status classification I or II- Patients scheduled to undergo elective laparoscopic cholecystectomy - BMI less than 35 kg/m - Patients who provide written informed consent to participate in the study

Exclusion criteria

Exclusion criteria: Patients unwilling to participate- Known allergy to local anaesthetic agents- Coagulopathy or those on anticoagulation therapy- Local infection at the injection site- History of chronic pain or current opioid usage- Conversion from laparoscopic to open cholecystectomy- Pregnant women

Design outcomes

Primary

Measure	Time frame
Postoperative Pain Intensity: Pain scores will be assessed using the Visual Analogue Scale (VAS) at multiple pre-defined time points within the first 24 hours after surgery in patients who receive either the EXORA or the subcostal TAP block Timepoint: 30 MINUTES 2,4,6,12 & 24 HOURS	—

Secondary

Measure	Time frame
Temporal Pain Assessment: To evaluate the duration of analgesic effect by measuring the time to first rescue analgesic request 2. Analgesic Consumption Analysis: To quantify and compare the total consumption of rescue analgesics in both groups during the first 24 hours postoperatively 3. Safety Profile Evaluation: To assess and compare the incidence of block-related complications and adverse events between the two techniques Timepoint: FIRST 24 HOURS	—

Measure

Time frame

Temporal Pain Assessment: To evaluate the duration of analgesic effect by measuring the time to first rescue analgesic request 2. Analgesic Consumption Analysis: To quantify and compare the total consumption of rescue analgesics in both groups during the first 24 hours postoperatively 3. Safety Profile Evaluation: To assess and compare the incidence of block-related complications and adverse events between the two techniques Timepoint: FIRST 24 HOURS

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Countries

India

Contacts

Public ContactLt Col Kapil Ashok Kulkarni

COMMAND HOSPITAL EASTERN COMMAND

akhilgoel.in@gmail.com9923686533

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026