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How Different Intracanal Medications Affect Pain After Root Canal Treatment in Diabetic Patients

Effect of Various Intracanal Medicaments on the Incidence and Intensity of Post Operative Pain in Patients with Diabetes Mellitus : A Randomized Controlled Clinical Trial - NIL

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/101168
Enrollment
100
Registered
2026-01-14
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E119- Type 2 diabetes mellitus without complications Health Condition 2: K049- Other and unspecified diseases ofpulp and periapical tissues

Interventions

Intervention1: Intracanal medicament: 1. Dexamethasone (Dexona 4 mg in the form of powder mixed with saline to form a moderately thick paste) 2. Diclofenac (Diclom 50mg in the form of powder mixed wit

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with controlled diabetes [HbA1C levels (6-7.65%)] Mature mandibular permanent teeth with symptomatic irreversible pulpitis. Teeth having sufficient tooth structure for adequate isolation. No history of previous endodontic therapy. No history of trauma to the involved tooth. Age criteria: between 18 to 60 years. Ability to understand and provide informed consent

Exclusion criteria

Exclusion criteria: immunocompromised patients, pregnant, lactating females. Patients who have a positive history of analgesic intake within past 3 days. Patients who have a positive history of antibiotics intake in the last month. Patients with known history of allergy to the drugs in study. Patients with radiographic evidence periapical pathology. Periodontally compromised teeth Calcified roots. Patients with known history of peptic ulcers or gastrointestinal bleeding. Neurologic patients. Psychiatric patients who are not able to rate the pain.

Design outcomes

Primary

MeasureTime frame
pain levels measured and comparedTimepoint: 4hrs, 8hrs, 12hrs, 24hrs, 48hrs

Secondary

MeasureTime frame
nilTimepoint: nil

Countries

India

Contacts

Public ContactSHREYA RASHI

SGT DENTAL COLLEGE

mamta.singla@sgtuniversity.org9891381349

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026