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Can Cooling the Bile Duct Opening Reduce Pancreatitis After ERCP?

Assessment of efficacy of additive effect of cooling of the papilla for preventing post-ERCP pancreatitis - NIL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/101115
Enrollment
500
Registered
2026-01-14
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K87- Disorders of gallbladder, biliarytract and pancreas in diseases classified elsewhere

Interventions

Intervention1: Ice-cold sterile water AND Indomethacin Suppository 10 mg: Papillary cooling using ice-cold sterile water (4 10 C), 250 mL irrigation over 3 5 minutes immediately after ERCP, in additio

Sponsors

Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age greater or equal to 18 years Patients undergoing ERCP with native papilla Ability to provide written informed consent

Exclusion criteria

Exclusion criteria: Age less than 18 years Prior sphincterotomy or altered anatomy Acute pancreatitis at presentation Chronic pancreatitis with calcification NSAID contraindication Pregnancy or lactation Refusal to consent

Design outcomes

Primary

MeasureTime frame
Incidence of post-ERCP pancreatitis as defined by revised Cotton criteriaTimepoint: 0, 2, 4, 6, 12, 24, 46, 72 hours—

Secondary

MeasureTime frame
Severity of post ERCP pancreatitis Serum amylase and lipase levels at 2, 4, 6 and 24 hours Other ERCP related complications Length of hospital stay Timepoint: 0, 2, 4, 6, 12, 24, 46, 72 hours—

Countries

India

Contacts

Public ContactDr Tryambak Samanta

Medical College, Kolkata

lipikakdb@gmail.com919433128722

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026