Health Condition 1: L700- Acne vulgaris
Conditions
Interventions
Intervention1: topical preparation containing enterococcus faecalis: A topical preparation containing probiotic enterococcus faecalis will be applied by the patient over the affected areas once daily
Sponsors
Indian Association of Dermatologist Venereologist and Leprologist research grant
Eligibility
Inclusion criteria
Inclusion criteria: Patients with mild to moderate acne (defined as acne grade 2.0 to 4.0 with at least 15 inflammatory and/or non-inflammatory lesions but no more than 1 nodules on the face) as per investigator global assessment score. Patients between the age group of 12-25 years. Willing to avoid use of other acne medications during the study Patients not on any topical antiacne preparation (retinoids, benzoyl peroxide or antimicrobial preparations) for past 2 weeks or any systemic treatment (retinoids or antimicrobial) for last 3 months. Patients who give written consent to enroll in the study
Exclusion criteria
Exclusion criteria: Severe acne (nodulocystic or conglobata) as per investigator global assessment score. Pregnant or breastfeeding Known hypersensitivity to any component of the study formulation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of percentage improvement in mean inflammatory and non-inflammatory acne lesion counts in mild to moderate acne patients after 12 weeks treatment with standard of care (benzoyl peroxide with gentle cleanser) versus add-on topical E.faecalis preparation.Timepoint: Baseline and after 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of side effects in mild to moderate acne patients after 12 weeks treatment with standard of care (benzoyl peroxide with gentle cleanser) versus add-on topical E.faecalis preparation.Timepoint: Baseline & 12 weeks | — |
Countries
India
Contacts
Public ContactDr Shiwangi Rana
All India Institute of Medical Sciences Gorakkhpur
Outcome results
None listed