Effect of Laser Treatment Used Along with Gum Surgery, With and Without a Natural Blood-Based Healing Material, on Gum Health and Inflammation Levels in Patients with Chronic Gum Disease.

Effect of Low Level Laser Therapy as an adjunct to open flap debridement with and without Albumin platelet rich fibrin on clinical parameters and gingival crevicular fluid interleukin 1beta level in chronic periodontitis patients. A clinico biochemical study - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/101075

Enrollment

Registered

2026-01-14

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: OPEN FLAP DEBRIDEMENT: All patients will be operated under local anaesthetic agent (2percent lignocaine containing 1/80,000 adrenaline). Anaesthesia will be administered by either nerve

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients who are systemically healthy. 2. Patients having minimum two sites in different quadrants with periodontal probing pocket depth (PPD) greater than or equal to 6mm and clinical attachment loss (CAL) greater than or equal to 3mm, having horizontal type of bone loss radiographically.

Exclusion criteria

Exclusion criteria: 1. Patients with the habits like smoking (current smokers), alcohol consumption and with systemic diseases like uncontrolled diabetes, hypertension, atherosclerosis, etc. 2. Patients with any periapical infections or large carious lesions. 3. Patients with history of antibiotics usage (within 3 months), or history of periodontal surgery in last six months. 4. Patients who are allergic to medications prescribed post- surgically. 5. Pregnant and lactating women. 6. Patients who exhibit non-compliant behaviour or physical disabilities. 7. Patients who cannot maintain oral hygiene or not available for follow up.

Design outcomes

Primary

Measure	Time frame
To assess Low- level laser therapy as an adjunct to open flap debridement on clinical parameters and GCF Interleukin-1beta level in chronic periodontitis patientsTimepoint: 4 months	—

Secondary

Measure	Time frame
To assess Low- level laser therapy as an adjunct to open flap debridement with Albumin platelet-rich fibrin on clinical parameters and GCF Interleukin-1beta level in chronic periodontitis patientsTimepoint: 4 months	—

Countries

India

Contacts

Public ContactDr Gayathri G V

Bapuji Dental College and Hospital

Gayathri_dental@rediffmail.com9886593224

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026