Health Condition 1: C57- Malignant neoplasm of other and unspecified female genital organs
Conditions
Interventions
Intervention1: Remifentanil-based anaesthesia (IV remifentanil bolus 1.5 g/kg followed by infusion 0.2 0.24 g/kg/min, titrated to SBP 20% of baseline): Group 1: Remifentanil)
Induction with propofo
Sponsors
Self
Eligibility
Inclusion criteria
Inclusion criteria: INCLUSION CRITERIA : Patient giving consent to involve in study Patient posted for elective gynaecological malignancy surgery needing general anaesthesia Patient aged between 18-65 years Patient with American Society of anaesthesiologists (ASA) Class 1 to Class 2
Exclusion criteria
Exclusion criteria: BMI >35 kg/m2 Uncontrolled comorbidities viz. diabetes, hypothyroidism, hypertension etc. H/O Cerebrovascular disease Patient with known or newly diagnosed coagulopathy Patient allergic to study drugs Patient with american society of anesthesiology (ASA) classification 3 or more Those schduled for undergoing emergency surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary objectives :To Assess total post operative analgesic consumption in 24 hours and time to first analgesic in opioid based and opioid free group.Timepoint: Just before induction (baseline) 5 minutes after induction 10 minutes after induction 15 minutes after induction 30 minutes after induction 60 minutes after induction | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to eye opening,extubation time & time to shifting to PACU NRS score at PACU admission Time to PACU discharge criteria (modified aldrete score ) Time to PACU discharge criteria (modified aldrete score) Incidence of complications.Timepoint: NRS pain score at PACU admission then every 15 minutes in PACU Time to PACU discharge measured as the duration from arrival in PACU until Modified Aldrete Score equal to or more than 9 | — |
Countries
India
Contacts
Public ContactDr Namita Gupta
Mahatma Gandhi Medical college and Hospital
Outcome results
None listed