Effect of Shunthi gokshur kwath with shunthi lepa and shunthi guduchi kwath with shunthi lepa in improving DAS 28 Score in Rheumatoid Arthritis.

A Randomized Comparative study to evaluate the efficacy of Shunthi Gokshur Kwath with Shunthi Lepa and Shunthi Guduchi Kwath with Shunthi Lepa in management of Rheumatoid Arthritis (Amavata) - nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/101038

Enrollment

Registered

2026-01-14

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M069- Rheumatoid arthritis, unspecified

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients of either sex aged 21 to 60 years. 2.Patients fulfilling ACR 2010 criteria of Rheumatoid arthritis (having a score greater or equal to 6/10). 3.Patients having the general clinical features of amavata as described in Madhav Nidan (Ma. Ni. 25/6to10) viz; Sandhi Saruja Shoth(pain in joints), along with one or more than one of the following clinical features a) Agnimandya (Poor digestion) b) Aruchi (Anorexia), c) Gaurava (heaviness of body) d) Utsaha hani (Lack of vigour) e) Mukha vairasya (Perverted taste). 4. Patients having blood pressure less than 150/90 mmHg. 5. Patients willing to provide written informed consent for participation in the study. 6.Patients who have not taken any DMARD or Glucocorticoid for more than 15 days or not taking any allopathic treatment at all. 7.Subjects who are not registered in any other research project. 8.Patients with firm home address and contact no. which is readily accessible during course of trial.

Exclusion criteria

Exclusion criteria: 1. Patients with crippling bone deformities. 2. Seriously ill and moribund patients. 3. Abnormal renal or hepatic functions, malignancy, cardiovascular disorder, HIV AIDS, etc. 4. Patients planning to conceive in near future (during course of trial) 5. Pregnant and lactating mothers. 6. Any major psychiatric illness. 7. Any other preexisting illness that will require surgery during course of trial. 8. Patients with any other concomitant Arthropathy like Ankylosing Spondylosis, Osteomyelitis, Gouty Arthritis, Neoplasm of spine, Fractures etc.

Design outcomes

Secondary

Measure	Time frame
I. CRP (Quantitative) II. RA Factor (Quantitative) III. ESR IV. SDAI V.As per General Sign & Symptoms of Amavata Sandhi Saruja Shotha (Inflammation of Joints) along with one or more than one of the following clinical features a)Vrishchika dansavata vedana (Pain like scorpion sting) b)Agnimandya (Poor digestion) c)Aruchi (Anorexia) d)Gaurava (Feeling of heaviness of the body) e)Utsaha Hani (Lack of vigour) f)Mukha Vairasya (Perverted taste) VI. Grade of Dhatu Samyata & Vikaropsaman Timepoint: assessed on screening,1st, 9th ,16th,23rd ,30th,45th ,60th day	—

Measure

Time frame

I. CRP (Quantitative) II. RA Factor (Quantitative) III. ESR IV. SDAI V.As per General Sign & Symptoms of Amavata Sandhi Saruja Shotha (Inflammation of Joints) along with one or more than one of the following clinical features a)Vrishchika dansavata vedana (Pain like scorpion sting) b)Agnimandya (Poor digestion) c)Aruchi (Anorexia) d)Gaurava (Feeling of heaviness of the body) e)Utsaha Hani (Lack of vigour) f)Mukha Vairasya (Perverted taste) VI. Grade of Dhatu Samyata & Vikaropsaman Timepoint: assessed on screening,1st, 9th ,16th,23rd ,30th,45th ,60th day

—

Primary

Measure	Time frame
Change in Disease Activity Score 28 (DAS28) from baseline is the primary outcome measureTimepoint: (assessed on Day screening,1st, 9th ,16th,23rd ,30th,45th ,60th)day	—

Countries

India

Contacts

Public ContactProf Dr Yogesh Kumar Pandey

Chaudhary Brahm Prakash Ayurved Charak Sansthan

dryogeshpandey@gmail.com9013858523

Outcome results