A study to compare how effectively different cleaning methods, including sound waves and light therapy, remove bacteria from root canals during dental treatment.

Clinical Study To Evaluate Antimicrobial Efficacy Of Passive Ultrasonic Irrigation, Conventional Irrigation And Photodynamic Therapy In Root Canal Treatment - Nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/100993

Enrollment

Registered

2026-01-13

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: Evaluation Of Disinfection Of Root Canal: With Different Irrigants And Different Irrigation Techniques Control Intervention1: With Using Conventional Irrigation, Passive Ultrasonic Irr

Eligibility

Inclusion criteria

Inclusion criteria: Patients Within The Age Group Of 18-65 Years Including Male & Female Both. Permanent Single Rooted Mature Tooth With Single Canal (Anterior And Premolar). Teeth Without Previous Restoration And Sufficient Coronal Structure For Isolation Temporization And Restoration. Teeth With Necrotic Or Infected Pulp.

Exclusion criteria

Exclusion criteria: Teeth With Fracture Lines, Open Apex Or Crack. Teeth With Periapical Abscess Or Cyst, Weeping Canals. Patients Requiring Antibiotic Premedication. Patients Who Declined To Give Consent For The Procedure. Teeth With Severe Canal Curvatures, Accessory Canals, Calcified Canals, Resorption (Internal And External), And Periodontal Diseases Were Excluded.

Design outcomes

Primary

Measure	Time frame
Increase In Depth Of Disinfection Of Root Canal After Subjecting The Teeth To Phothodynamic (PDT)t Therapy With Indocyanine Green And Decreased In Bacterial Load After Biomechanical Preparation.Timepoint: Indocyanine green mediated photodynamic therapy will be applied in root canals using a 1 W continuous laser in three 8-second intervals. Baseline (S1) and post-treatment (S2) bacterial samples will be collected, cultured on brain heart infusion agar, and incubated for 24 hours. Antimicrobial efficacy will be evaluated by comparing CFU counts and statistically analyzing the reduction in bacterial load.	—

Measure

Time frame

Increase In Depth Of Disinfection Of Root Canal After Subjecting The Teeth To Phothodynamic (PDT)t Therapy With Indocyanine Green And Decreased In Bacterial Load After Biomechanical Preparation.Timepoint: Indocyanine green mediated photodynamic therapy will be applied in root canals using a 1 W continuous laser in three 8-second intervals. Baseline (S1) and post-treatment (S2) bacterial samples will be collected, cultured on brain heart infusion agar, and incubated for 24 hours. Antimicrobial efficacy will be evaluated by comparing CFU counts and statistically analyzing the reduction in bacterial load.

—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Kailash Attur

Narsinhbhai Patel Dental College And Hospital,Sankalchand Patel University,Visnagar

atturkailash@gmail.com9727752499

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026