A Study on the Effectiveness of Combined Oral and Nasal Ayurvedic Treatment in Patients Suffering from Hypothyroidism.

Add on effect of oral Kanchan Gutika Guggulu with Nasya of Katutumbi Tailam in the management of Kaphaj Galganda w.s.r. to hypothyroidism in the age group of 19 to 60 years(RCT). - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/100935

Enrollment

Registered

2026-01-13

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E039- Hypothyroidism, unspecified Health Condition 2: E02- Subclinical iodine-deficiency hypothyroidism

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients who are recently diagnosed and known case of Hypothyroidism on active medication. 2.Patients having signs and symptoms of hypothyroidism. 3.Age between 19 to 60 years irrespective of any gender,caste,religion and socioeconomic status. 4.Serum T3 Below or normal Range i.e. (75 to 175 ng per dL or below) T4 levels normal or below i.e. ( 4 to 11 micro gm per dL or below ), and serum TSH levels above the normal range i.e. ( more than 5.5 micro gm per dL). 5. Patients who are fit for Nasya Karma. 6. Patients who are willing to participate in the study and able to provide written consent.

Exclusion criteria

Exclusion criteria: 1. Patients below 19 years and above 60 years of age. 2. Patients having known case of Hyperthyroidism. 3. Pregnant or Lactating Women. 4. If patient undergone any Thyroid surgery. 5. Patients having any systemic disease like, Kochs disease , COPD and Carcinoma , HIV. 6. Patients having Myxedema coma (complication of longstanding untreated hypothyroidism. 7. History of hypersensitivity or allergy to any Ingredient in kanchan gutika Guggulu or Katutumbi Tailam. 8. Patients having acute infections or nasal pathology that are contraindicates Nasya karma.

Design outcomes

Primary

Measure	Time frame
Patients with clinical signs and symptoms of Kaphaj Galganda as described 1. Sthir Galpradesh Shwayathu (Neck Swelling anteriorly on thyroid gland) 2. Mukha Shotha(Puffiness of face) 3. Ruja ( Pain at the site of swelling) 4. Daurbalya or Aalasya (Lethargy and weakness) 5. Khalitya (Hair loss and Alopecia) 6. Shramashwasa (Dyspnea on exertion) 7. Asraddha and Aruchi (loss of appetite) 8. Tvaka Rukshta (Dry or Coarse skin ) 9. Sarvang Graha (Muscle stiffness) 10. Gadgadvakta (Hoarseness of voice) 11. Bharvrudhi (Weight gain) 12. Irregular Menstrual cycle I.e. interval between two cycles in females.Timepoint: 8th,15th,22rd,29th,36th,45th,60th,75th,90th	—

Measure

Time frame

Patients with clinical signs and symptoms of Kaphaj Galganda as described 1. Sthir Galpradesh Shwayathu (Neck Swelling anteriorly on thyroid gland) 2. Mukha Shotha(Puffiness of face) 3. Ruja ( Pain at the site of swelling) 4. Daurbalya or Aalasya (Lethargy and weakness) 5. Khalitya (Hair loss and Alopecia) 6. Shramashwasa (Dyspnea on exertion) 7. Asraddha and Aruchi (loss of appetite) 8. Tvaka Rukshta (Dry or Coarse skin ) 9. Sarvang Graha (Muscle stiffness) 10. Gadgadvakta (Hoarseness of voice) 11. Bharvrudhi (Weight gain) 12. Irregular Menstrual cycle I.e. interval between two cycles in females.Timepoint: 8th,15th,22rd,29th,36th,45th,60th,75th,90th

—

Secondary

Measure	Time frame
1.T3(normal or below normal range i.e. 75 to 175 ng per dL) 2.T4(normal or below normal range i.e. 4 to 11 micro gm per dL and less) 3.TSH(more than 5.5 micro gm per dL)Timepoint: 0th,90th	—

Countries

India

Contacts

Public ContactDr Subhash Bhikaji Jamdhade

Dayabhai Maoji Majithiya Ayurved Mahavidyalaya and L K Ayurved Rugnalaya Yavatmal

drsubhashjamdhade@gmail.com9822201196

Outcome results