A study comparing two types of clear aligners for correcting crowded lower front teeth in adults

Evaluation of the efficacy of Direct 3D-printed aligners with that of Thermoformed aligners in resolving lower anterior crowding among adults- A single-blind randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/100895

Enrollment

Registered

2026-01-12

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K088- Other specified disorders of teethand supporting structures

Interventions

Intervention1: Direct 3D-Printed Aligners: After the pre-treatment evaluation Digital intraoral scans will be taken using a high-precision intraoral scanner (Helios-500, Changzhou Sifary Medical Tech

Eligibility

Inclusion criteria

Inclusion criteria: Patients with fully erupted permanent dentition (excluding third molar) irrespective of gender Healthy, compliant and motivated patients who can visit clinic regularly. Angle s class I malocclusion with Mild to Moderate lower anterior crowding. Non extraction treatment plan. No history of previous orthodontic treatment.

Exclusion criteria

Exclusion criteria: Gross gingival/periodontal problems in lower anterior teeth Presence of dental anomalies in the lower anterior teeth Patients with craniofacial syndromes or genetic disorders affecting dentofacial development Prosthetic replacements in lower anterior teeth

Design outcomes

Primary

Measure	Time frame
Change in the Little s Irregularity IndexTimepoint: at baseline (T0), 2 months(T1), 4 months(T2) and post-treatment(T3)	—

Secondary

Measure	Time frame
Rate of correction of crowdingTimepoint: 4 weeks, 8 weeks, 12 weeks, 16 weeks ,20 weeks, 24 weeks;Treatment Duration ComparisonTimepoint: 24 weeks;Comparison of Number of Aligners UsedTimepoint: 24 weeks;Change in Mandibular Incisor Inclination (IMPA)Timepoint: 24 weeks;Change in mandibular inter-canine widthTimepoint: 24 weeks;Amount of Interproximal Reduction (IPR)Timepoint: 24 weeks	—

Countries

India

Contacts

Public ContactDr Praveen S

Government dental college, Kozhikkode

Orthonair@gmail.com9846274491

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026