Study between Tamsulosin and in Combination with Deflazacort in Distal Ureteric Calculus less than 10mm

Tamsulosin alone and in Combination with Deflazacort for Medical Expulsion therapy of Distal Ureteric Calculus less than 10mm: A Randomized Controlled Study - MET

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/100858

Enrollment

162

Registered

2026-01-12

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N201- Calculus of ureter

Interventions

Intervention1: Tamsulosin + Deflazacort: 0.4mg + 30mg per oral for 3 weeks Control Intervention1: Tamsulosin: 0.4mg per oral for 3 weeks

Eligibility

Inclusion criteria

Inclusion criteria: 1) All patients who report to emergency/ Urology OPD with ureteric calculi 10 mm or less in size willing to give consent for the study

Exclusion criteria

Exclusion criteria: 1) Patient with urinary tract infection (based on urine routine analysis and fever),2) Uncontrolled pain,3) Impaired kidney function (Serum creatinine greater than 1.4 mg/dl), 4) Solitary kidney,5) Diabetic patients(HbA1c greater than 7%)

Design outcomes

Primary

Measure	Time frame
To assess stone expulsion rates on treatment with alpha blockers (Tamsulosin) and in combination with corticosteroids (Tamsulosin + Deflazacort) in patients diagnosed with distal ureteric calculus less than or equal to 10mmTimepoint: 3 weeks	—

Secondary

Measure	Time frame
To assess stone expulsion based on size of stone (less than 5mm, 5-10 mm)Timepoint: 3 weeks;Quantification of Analgesics used (using analgesic quantification score)Timepoint: 3 weeks;Average time of stone clearance (NCCT KUB on h/o passage of stone or at 03 weeks whichever is earlier).Timepoint: 3 weeks	—

Countries

India

Contacts

Public ContactPusarla Subash Chandra

MBBS, MS(Gen Surgery), MRCS(Glasgow), Mch(Urology), FRCS(Urology)(Glasgow)

sunil.pillai@manipal.edu9731855209

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026