Health Condition 1: S00-T88- Injury, poisoning and certain other consequences of external causes
Conditions
Interventions
Intervention1: Wet Collagen Sheet: Collagen scaffold in hydrated form available in various sizes to be applied over the graft donor sites
Duration will be one time.
Control Intervention1: Dry Collage
Sponsors
ED and CEO
Eligibility
Inclusion criteria
Inclusion criteria: Patients undergoing split-thickness skin grafting for burns sequelae and trauma. Maximum donor site size or skin requirement: 15 cm x 20 cm. Patients providing informed consent to participate in the study.
Exclusion criteria
Exclusion criteria: oKnown allergy or hypersensitivity to collagen-based products. o Donor site size exceeding or skin requirement more than15 cm x 20 cm. o Patient with Serum Album levels less than 3 gm/dl and Hb less than 10gm /dl o Presence of systemic conditions affecting wound healing, such as uncontrolled diabetes or peripheral vascular disease. o Use of immunosuppressive medications within six months prior to enrollment. o Poorly controlled or active infections at the donor site.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Pain Scores: Measured using the Visual Analog Scale (VAS) at days 1, 3, 7, & 14 post-operativelyTimepoint: Day 1,3,7 & 14;Complications: Incidence of infection (ASEPSIS scoring), hypertrophic scarring (Vancouver Scar Scale), & delayed healing.Timepoint: Days 1, 3, 7, 14; , Months 1, 4, 6, 8 | — |
Primary
| Measure | Time frame |
|---|---|
| Healing Time, Time (in days) to achieve more than 95 percent epithelialization, assessed by digital planimetry and clinical evaluation.Timepoint: Baseline, Pre Surgery, Day 1,3,7, 14, and Months 1,4,6,8. | — |
Countries
India
Contacts
Public ContactDr Al Iqyan Fidvi
AIIMS, NAgpur
Outcome results
None listed