Health Condition 1: K029- Dental caries, unspecified
Conditions
Interventions
Intervention1: LOCAL ANAESTHETIC AGENTS: Local anaesthetic (LA) agents are drugs that reversibly block nerve conduction when applied locally, producing loss of sensation without loss of consciousness.
Sponsors
UTTARANCHAL DENTAL AND MEDICAL RESEARCH INSTITUTE
Eligibility
Inclusion criteria
Inclusion criteria: 1. Adults 18 to 60 years of age. 2. Patients diagnosed with irreversible pulpitis requiring a root canal procedure in their mandibular molars. 3. No prior endodontic treatment. 4. Not on interacting medications. Not currently taking medications that significantly interact with epinephrine or local anesthetics. 5. Ability to provide informed consent
Exclusion criteria
Exclusion criteria: 1. Known allergy or hypersensitivity to amide-type local anesthetics, epinephrine, or any component of the study formulations (e.g., sulphites). 2. Patients with significant systemic diseases (ASA Class III or above) such as uncontrolled hypertension, diabetes, cardiovascular disease, hepatic or renal impairment. Presence of acute swelling, abscess, cellulitis, or trismus in the area of interest that may alter anesthetic diffusion or success. Patients on anticoagulants, antiplatelet therapy, or having coagulopathies, increasing risk of bleeding or hematoma with injection. Pregnant or lactating women will be excluded from the study due to potential risks associated with local anaesthetic administration and ethical considerations regarding fetal exposure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in Heft Parker Visual Analogue Score (HPVAS 0-170) pre and intra-operative.Timepoint: 10 minutes after administration of local anaesthesia and 10 minutes during procedure | — |
Secondary
| Measure | Time frame |
|---|---|
| NILTimepoint: NIL | — |
Countries
India
Contacts
Public ContactDR RUDRA SANJEEV NARVEKAR
UTTARANCHAL DENTAL & MEDICAL RESEARCH INSTITUTE
Outcome results
None listed