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Observational Research involving South Indian patients undergoing stomach biopsy to identify H. pylori infection and biofilm formation.

Exploring the Molecular Variability in the Pathogenic Cascades of Helicobacter pylori in Human Biopsy samples of South India and their related Biofilm Mechanism - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/01/100727
Enrollment
400
Registered
2026-01-09
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K296- Other gastritis

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Dr Vinay Alva
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: consecutive symptomatic patients both males and females aged 20 to 60 years attending the endoscopy unit of Alvas Health Centre Moodubidire for Twelve months

Exclusion criteria

Exclusion criteria: Subjects contra-indicated for endoscopy will be excluded.

Design outcomes

Primary

MeasureTime frame
1 Design and development of newer therapeutics for H pylori infections 2 Design of newer biomarkers for diagnosis and molecular detection kits for H pylori 3 Understanding the molecular signaling cascades of H pylori in biofilm form which will aid in the development of better therapeutics.Timepoint: Timepoints: Baseline (Week 0), followed by assessments at Week 4, 8, 12, 16, 20, 24, 28, 32, 36, 40, 44, 48, and Week 52.

Secondary

MeasureTime frame
Design of newer biomarkers for diagnosis & molecular detection kits for H pylori Understanding the molecular signaling cascades of H pylori in biofilm form which will aid in the development of better therapeutics.Timepoint: Baseline (Week 0 Initial molecular profiling), Week 12 Biomarker discovery, Week 24 Analytical validation, Week 36 Prototype kit development, Week 48 Final validation.

Countries

India

Contacts

Public ContactDr Rahul Kunkulol

Pravara Institute of Medical Sciences (DU)

rahul4420@yahoo.com9637549119

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026