A research study that aims to comparative study of sevoflurane and isoflurane on hemodynamic stability on patients undergoing laparoscopic surgery. This study will help us understand which medication is more effective in reducing the stress response associated with these procedures.

COMPARATIVE STUDY OF SEVOFLURANE AND ISOFLURANE ON HEMODYNAMIC STABILITY ON PATIENTS UNDERGOING LAPAROSCOPIC SURGERY: A RANDOMIZED CLINICAL TRIAL - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/100715

Enrollment

Registered

2026-01-09

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis Health Condition 2: K802- Calculus of gallbladder without cholecystitis Health Condition 3: K811- Chronic cholecystitis Health Condition 4: K811- Chronic cholecystitis Health Condition 5: K353- Acute appendicitis with localizedperitonitis

Interventions

Intervention1: INHALATIONAL AGENT ISOFLURANE: Study participants will receive isoflurane after securing airway by endotracheal tube,The anaesthetic concentration was adjusted to maintain minimum alveo

Eligibility

Inclusion criteria

Inclusion criteria: Patients of either sex Patients with ASA physical grade 1 and 2 Patients of age group 18 to 60 years

Exclusion criteria

Exclusion criteria: Difficult airway Uncontrolled Hypertension Uncontrolled Diabetes mellitus Ischemic heart disease Severe Renal disease Cerebrovascular disease Patients on beta blockers, alpha blockers Bronchial Asthma Allergy to study drugs

Design outcomes

Primary

Measure	Time frame
To evaluate hemodynamic stability during the induction, maintenance, and emergence phases of anesthesiaTimepoint: vitals including pulse rate, blood pressure, mean arterial pressure, and peripheral oxygen saturation assesed during operative period till 45 minutes.	—

Secondary

Measure	Time frame
emergence time, extubation time, time to obey verbal commands, and time to achieve an Aldrete score of 9 or more than 9.Timepoint: patient have to be monitored for 30 minutes in post operative room	—

Countries

India

Contacts

Public ContactJiwanshu

Regional institute of medical sciences

dranitadevin@gmail.com8787458045

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026