Health Condition 1: C55- Malignant neoplasm of uterus, partunspecified Health Condition 2: N859- Noninflammatory disorder of uterus, unspecified
Conditions
Interventions
Control Intervention1: iv ibuprofen: premptive iv ibuprofen given half an hour before spinal anaesthesia
Control Intervention2: iv paracetamol: premptive iv paracetamol given half an hour before spina
Sponsors
mimer medical college talegaon
Eligibility
Inclusion criteria
Inclusion criteria: Female patients aged 30-60 years of undergoing Total Abdominal Hysterectomy willing to participate. ASA grade I and II
Exclusion criteria
Exclusion criteria: 1. History of allergic reactions to paracetamol or Ibuprofen, 2. History of usage of paracetamol, Ibuprofen, in the 48 hours 3. Not willing to participate 4. Patient with severe hepatic or renal impairment & Cardiovascular system illness. 5. Patient who are unable to interpret VAS [visual analogue scale] for pain. 6. Patients on chronic analgesic property 7. History of GI bleeding or Peptic Ulcer Disease 8. History of Bronchial Asthma 9. Bleeding Disrorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate and compare total duration of analgesia with single dose pre-emptive IV ibuprofen vs IV paracetamolTimepoint: assessed as time to first rescue dose of analgesia required post- operatively | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare Total number of rescue doses of analgesia required in 24 hours To compare intra operative Shivering associated with both the drugs Adverse effects if anyTimepoint: Total number of rescue analgesic doses in post-operative period will also be noted for 24 hours 2.intraoperative shivering will be asessed with scale | — |
Countries
India
Contacts
Public ContactISHA MANRESH JAISWAL
MIMER medical college talegaon
Outcome results
None listed