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Effect of Adding Dexamethasone to Scalp Nerve Block for Pain Relief After Brain Surgery

Evaluation of dexamethasone as an adjuvant for scalp nerve block for post operative analgesia following supratentorial craniotomy - NIL

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/100662
Enrollment
60
Registered
2026-01-09
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G00-G99- Diseases of the nervous system

Interventions

Intervention1: the scalp nerve block will be done before incision to patients undergoing supratentorial craniotomy: the scalp nerve block will be done with 20ml of 0.5% bupivacaine,1ml of 100mcg/ml e

Sponsors

pt. B.D. Sharma PGIMS Rohtak
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American society of anaesthesiologist physical status classification 1-3, Glassgow coma scale(GCS) score of 15/15 schedule to undergo elective supratentorial craniotomy under general anaesthesia

Exclusion criteria

Exclusion criteria: 1)Patients having contraindications to regional anaesthesia 2)coagulation abnormalities 3)active infection at injection site 4)chronic pain syndromes 5)chronic opioid use(more than 2 weeks or 3 days per week for more than 1 month) 6)extreme body mass index( 35) 7)refusal or inability of patient or legal guardian to provide inform consent

Design outcomes

Primary

MeasureTime frame
To compare Visual Analogue Scale(VAS) for pain following scalp nerve block with local anaesthetic agents with or without addition of dexamethasone in patients undergoing supratentorial craniotomy under general anaesthesiaTimepoint: vas scale for pain assessment will be done at baseline, 24hrs and 3 months

Secondary

MeasureTime frame
intraoperatice heamodynamic parameterTimepoint: pre induction,before block,after block, before incision, after incision, 15 min,30 min, 1 hr, 2hr after incision;duration of postoperative analgesiaTimepoint: ;24 hrs analgesic requirementTimepoint: ;Demand to 1st rescue analgesiaTimepoint: ;postoperative nausea and vomitingTimepoint:

Countries

India

Contacts

Public ContactDr Nitish agarwal

pt. B.D. Sharma PGIMS Rohtak

nitishagarwal18nov1999@gmail.com8708537472

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026