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comparison of three different treatments for patients with oral lichen planus

COMPARATIVE EVALUATION OF EFFICACY OF INTRALESIONAL LOW MOLECULAR WEIGHT HEPARIN, INTRALESIONAL INJECTION OF TRIAMCINOLONE ACETONIDE AND PHOTO-BIOMODULATION IN ORAL LICHEN PLANUS: A RANDOMIZED CLINICAL TRIAL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/100564
Enrollment
72
Registered
2026-01-08
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L99- Other disorders of skin and subcutaneous tissue in diseases classified elsewhere

Interventions

Intervention1: Intralesional injection of low molecular weight heparin: Group A will consist of 24 patients clinically diagnosed with symptomatic oral lichen planus. In these 24 patients intralesion

Sponsors

subharti dental college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Above 18 years of age. 2. Patients clinically diagnosed with symptomatic oral lichen planus. 3. Patients who will give consent for the treatment.

Exclusion criteria

Exclusion criteria: 1. Hospitalized patients and pregnant females. 2. Kidney and liver failure patients. 3. History of bleeding diathesis, uncontrolled hypertension, cerebrovascular accident, peptic ulcer. 4. Hypersensitivity to heparin and heparin derivatives and a history of heparin-induced thrombocytopenia.

Design outcomes

Primary

MeasureTime frame
reduction in burning sensation measured by visual analog scale and clinical improvement in lesion size and appearance measured by thongprasom scoring criteria and improvement in quality of life which is measured by American chronic pain associationTimepoint: 6 month and 1 year

Secondary

MeasureTime frame
Recurrence rateTimepoint: 6 months after completion of treatment

Countries

India

Contacts

Public ContactDRSANGEETA MALIK

SUBHARTI DENTAL COLLEGE AND HOSPITAL

drswatig@rediffmail.com9634927286

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026