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A study to compare pain following single-visit root canal treatment with different cold treated root canal irrigants

Comparative evaluation of post-operative pain following single-visit root canal treatment with cryomodified root canal irrigants: an in vivo study - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/100546
Enrollment
80
Registered
2026-01-08
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: Evaluation of post-operative pain: Evaluation of post-operative pain by using different root canal irrigants at 6, 12, 24, 48 hours Control Intervention1: at different temperatures: To

Sponsors

Dr Ketaki Gundawar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: The patient requiring endodontic therapy. Single rooted permanent teeth that will be diagnosed with symptomatic irreversible pulpitis. Healthy patients without systemic disease. Patients with pain score ranging from moderate to severe (3 10) on a Visual Analog Scale (VAS) (0 10) Ability to fill the root canals in a single visit.

Exclusion criteria

Exclusion criteria: Patient who are medically compromised. Pregnant patients. Patients on antibiotic therapy. Patients on analgesics. Teeth with incomplete apex formation or root resorption. Teeth with anatomical or morphological anomalies. Teeth with calcified canals. Teeth with sinus opening. Teeth with periapical pathology.

Design outcomes

Primary

MeasureTime frame
Incidence of post operative pain will be less using Twin Kleen(etidronic acid)Timepoint: Pain will be evaluated at 6, 12, 24, 48 hours

Secondary

MeasureTime frame
Incidence of post operative pain will be less using cryotreated(0 degree Celcius)Twin Kleen(etidronic acid)Timepoint: Pain will be evaluated at 6, 12, 24, 48 hours

Countries

India

Contacts

Public ContactDr Kailash Attur

Narsinhbhai Patel Dental College and Hospital

atturkailash@gmail.com9727752499

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026