A Clinical study to compare the efficacy of Vaitarana and Siddha Basti mentioned by Vangasena along with Dhanyamla Dhara in Amavata(Rheumatoid Arthritis).

A Randomized open labelled clinical study to compare the efficacy of Vangasenokta Siddha Basti and Dhanyamla Dhara with Vangasenokta Vaitarana Basti and Dhanyamla Dhara in the management of Amavata Vis-a-vis Rheumatoid Arthritis. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/100529

Enrollment

Registered

2026-01-08

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M069- Rheumatoid arthritis, unspecified

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1)Subjects of age group between 20 to 60 yrs, of both genders with chronicity equal to or less than five-year duration will be selected for the study. 2)Subjects of Amavata diagnosed on the basis of signs & symptoms described in Ayurvedic classics will be selected for the study. 3)Subjects diagnosed as Amavata with features of Rheumatoid arthritis as specified in European League Against Rheumatism/ American College of Rheumatology 2010 criteria that is 2010 ACR-EULAR diagnostic criteria24 will be selected for the study. 4)Subjects indicated for Basti Karma and Dhanyamla Dhara will be selected for the study. 5)Considering disease activity and functional impairment STAGE-1, STAGE-2 6)Subjects voluntarily willing to give written consent and participate in the study.

Exclusion criteria

Exclusion criteria: 1)Subjects of both genders with chronicity of disease more than 5 years with any joint deformity. 2)Subjects with any systemic disease or condition that would potentially interfere with the course of treatment. 3)Subjects contraindicated for Basti Karma and Dhanyamla Dhara. 4)Subjects with the signs and symptoms of Pravruddha Amavata with joint deformities STAGE-3, STAGE-4 5)Pregnant and lactating women.

Design outcomes

Primary

Measure	Time frame
Significant decrease in symptoms of Amavata vis-a-vis Rheumatoid arthritis assessed based on subjective parameters like Sandhishoola, Sandhistabdhata, Sandhishopha and other Samanya Lakshanas like Angamarda, Aruchi, Trushna etc., ) and objective parameters ( like tenderness in joints, warmth in joints, Disease activity score 28 or DAS28, general functional capacity and Barthel s index)Timepoint: all the parameters will be assessed at 3 different time points, namely 0th day, 8th day and 16th day.	—

Measure

Time frame

Significant decrease in symptoms of Amavata vis-a-vis Rheumatoid arthritis assessed based on subjective parameters like Sandhishoola, Sandhistabdhata, Sandhishopha and other Samanya Lakshanas like Angamarda, Aruchi, Trushna etc., ) and objective parameters ( like tenderness in joints, warmth in joints, Disease activity score 28 or DAS28, general functional capacity and Barthel s index)Timepoint: all the parameters will be assessed at 3 different time points, namely 0th day, 8th day and 16th day.

—

Secondary

Measure	Time frame
Generation of in-depth analysed data on the different aspects of the disease. Generation of data on quality of life with the test treatment modalities assessed based on Barthel s index. Generation of data on possible unexpected/adverse drug reactions or events. Timepoint: 0th day, 8th day, 16th day	—

Countries

India

Contacts

Public ContactDr Madhushree H.S.

Sri Sri College of Ayurvedic science and Research Hospital

drmadhushreehs@rediffmail.com9916058006

Outcome results