comparison of lung ventilation with different pressure levels in laparoscopic surgery

Comparative assessment of electrical impedance tomography guided regional ventilation with different levels of PEEP in laparoscopic cholecystectomy: A Randomised Control Trial. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/100463

Enrollment

Registered

2026-01-07

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K87- Disorders of gallbladder, biliarytract and pancreas in diseases classified elsewhere

Interventions

Intervention1: Group P10 = PEEP 10 cmH2O: Patients will be ventilated with a tidal volume (Vt) of 6 8 mL/kg PBW with FiO2 0.4 0.5 and minute ventilation will be titrated to achieve the end-tidal carbo

Eligibility

Inclusion criteria

Inclusion criteria: Age- 18-65 years Both genders American society of anaesthesiologist (ASA) physical status I-II Posted for routine lap cholecystectomy

Exclusion criteria

Exclusion criteria: Patient refusal Cardiopulmonary diseases Pregnancy & lactating mothers Conversion into open cholecystectomy due to any reason Gross anatomical deformities of the chest Patients with chronic obstructive pulmonary disease

Design outcomes

Primary

Measure	Time frame
1. Change in the regional distribution of tidal variation (TV ROI %) 2. Regional change of end expiratory lung impedance (EELI - % win /% loss) Timepoint: 1. Change in the regional distribution of tidal variation (TV ROI %) 2. Regional change of end expiratory lung impedance (EELI - % win /% loss)	—

Secondary

Measure	Time frame
1. Number of patients requiring oxygen supplementation in the postoperative periodTimepoint: Regional lung ventilation, collapse and overdistension will be monitored by using Drager Pulmovista 500 (model, country name) at pre induction (T0), induction (T1), during abdominal CO2 insufflation(T2) , at the end of the surgery(T3) and in the post operative period at 15 minutes(T4),30 minutes(T5) and 1 hour(T6). Recruitment will be given based on the regional ventilation, collapse and overdistension as seen on EIT monitor .RAMP technique will be used for recruitment that is progressive increase in airway pressure up to 40 cm H2O reached at 40 seconds after the onset of inflation.	—

Measure

Time frame

1. Number of patients requiring oxygen supplementation in the postoperative periodTimepoint: Regional lung ventilation, collapse and overdistension will be monitored by using Drager Pulmovista 500 (model, country name) at pre induction (T0), induction (T1), during abdominal CO2 insufflation(T2) , at the end of the surgery(T3) and in the post operative period at 15 minutes(T4),30 minutes(T5) and 1 hour(T6). Recruitment will be given based on the regional ventilation, collapse and overdistension as seen on EIT monitor .RAMP technique will be used for recruitment that is progressive increase in airway pressure up to 40 cm H2O reached at 40 seconds after the onset of inflation.

—

Countries

India

Contacts

Public ContactSamarjit Dey

AIIMS Mangalagiri

drsamarjit@aiimsmangalagiri.edu.in7805920791

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026