Health Condition 1: N998- Other intraoperative and postprocedural complications and disorders of genitourinary system
Conditions
Interventions
Intervention1: Injection Cefuroxime: single dose of pre operative cefuroxime 1.5 Gram will be given to the intervention group
Control Intervention1: Injection Cefuroxime + Oral cefuroxime: a single p
Sponsors
AIIMS Bhubaneswar
Eligibility
Inclusion criteria
Inclusion criteria: Undergoing elective TURP, TURBT, OIU, BNI, or CLT Preoperative sterile urine culture (within 7 days prior to surgery) Willing and able to provide written informed consent
Exclusion criteria
Exclusion criteria: 1. Evidence of preoperative UTI or positive urine culture 2. Immunocompromised status (e.g., HIV with CD4 3. Chronic kidney disease (Stage IV or above) 4. Known allergy to cefuroxime or beta-lactam antibiotics 5. Patients requiring intraoperative or postoperative antibiotic escalation for other complications
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the rates of significant bacteriuria on POD 3 urine cultures in both groupsTimepoint: To compare the rates of significant bacteriuria on POD 3 urine cultures in both groups | — |
Secondary
| Measure | Time frame |
|---|---|
| Re-admission rate within 30 days for urinary sepsis or related complicationsTimepoint: within 30 days postop;incidence of asymptomatic bacteriuriaTimepoint: within 30 days post op;adverse drug reactionTimepoint: after giving antibitic, till hospital stay;emergence of antibiotic resistant organismsTimepoint: in post operative cultures | — |
Countries
India
Contacts
Public ContactSrujan S Dharap
AIIMS Bhubaneswar
Outcome results
None listed