Health Condition 1: E00-E89- Endocrine, nutritional and metabolic diseases
Conditions
Interventions
Intervention1: Early-Start GnRH Antagonist Protocol (Day 1 Administration): The administration of the GnRH antagonist is shifted from the conventional mid-stimulation phase to the very first day of th
Sponsors
SELF (Ghosh Dastidar Institute For Fertility Research Pvt Ltd)
Eligibility
Inclusion criteria
Inclusion criteria: PCOS patients undergoing IVF
Exclusion criteria
Exclusion criteria: Patients with grade III-IV endometriosis, concurrent severe male factor infertility, or history of previous ovarian surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of clinical pregnancy rate between the two groups with Antagonist administration from day 1 of IVF versus standard flexible day 5/6.Timepoint: 1. Recruitment of participants and randomisation- 0-6 months 2. Conduct and completion of study: 6-12 months 3. Data organisation and curation: 12-18 months 4. Data analysis and publication:12-18 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare number of oocytes, proportion of fertilized oocytes, and proportion of top quality embryos achieved between 2 groupsTimepoint: 1. Recruitment of participants and randomisation- 0-6 months 2. Conduct and completion of study: 6-12 months 3. Data organisation and curation: 12-18 months 4. Data analysis and publication:12-18 months | — |
Countries
India
Contacts
Public ContactBiswanath Ghosh Dastidar
Ghosh Dastidar Institute For Fertility Research Pvt Ltd
Outcome results
None listed