Comparison of Ultrasound Guided Obturator Nerve Block versus Intravesical Instillation of Alkalinized 1% Lignocaine to prevent Obturator Jerk during Transurethral Resection of Bladder Tumor

Comparison of Ultrasound Guided Obturator Nerve Block using 10ml of 1 percent lignocaine and 3ml of 8.4 percent sodium bicarbonate versus Intravesical Instillation of Alkalinized 10ml of 1 percent lignocaine and 3ml of 8.4 percent sodium bicarbonate to prevent Obturator Jerk during TURBT: A Randomized Controlled Trial - NILL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/100393

Enrollment

Registered

2026-01-06

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C672- Malignant neoplasm of lateral wallof bladder Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: USG Guided Obturator Nerve Block: USG guided Obturator Nerve Block performed using 10ml of 1% lignocane and 3ml of 8.4% sodium bicarbonate to prevent obturator jerk for lateral bladder

Eligibility

Inclusion criteria

Inclusion criteria: Age: 18 75 years ASA physical status I III Elective TURBT under spinal anesthesia Tumor involving the lateral bladder wall

Exclusion criteria

Exclusion criteria: 1.Allergy to local anesthetics (amide type). 2.Coagulopathy or on anticoagulants that cannot be safely stopped. 3.Infection at block/instillation site. 4.Pre-existing lower limb neuropathy affecting adductor function. 5.Pregnant or breastfeeding patients. 6.Patients requiring general anesthesia for other indications. 7.Large bladder perforation risk anticipated (surgeon judgement).

Design outcomes

Primary

Measure	Time frame
To compare the incidence of obturator jerk during TURBT in patients receiving either: 1.Ultrasound-guided obturator nerve block (ONB), or 2.Intravesical instillation of lignocaine (10 ML 1% Lignocaine with 3 ml 8.4% sodium bicarbonate) under spinal anaesthesia. Timepoint: over a period of 1 year	—

Secondary

Measure	Time frame
1.To grade the severity of obturator jerk using a standardized scoring system. 2.To compare the surgeon s satisfaction scores between the two groups using a Likert scale. 3.To evaluate & compare the rate of intraoperative complications, including bladder perforation, & conversion to general anaesthesia. 4.To compare the incidence of catheter related bladder pain Timepoint: over a period of 1 year	—

Countries

India

Contacts

Public ContactMamta Chadha

Northern Railway Central Hospital New Delhi

mamtachadha@rediffmail.com9717630526

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026