Health Condition 1: G939- Disorder of brain, unspecified
Conditions
Interventions
Intervention1: onsd: ONSD will be evaluated using a portable high-resolution ocular ultrasound (Sonosite) at the
bedside.
Measurements will be taken 3 mm posterior to the globe, and the average of t
30% (20%): good reactivity
20% (12%): weak reactivity
12% (5%): very weak reactivity
5%: reactivity: null, and the Qualitative Pupillometry Index, (QPI) [0-1-2: Nonreactive/Weak
3: Reduced
4-5: Good/Very Good]. Measurements will be performed at baseline, 24 hours, 48 hours, and on 72 hours post-admission.
(TOTAL 4 DAYS)
Intervention3: nil: nil
Control Intervention1: nil: nil
Sponsors
AIIMS
Eligibility
Inclusion criteria
Inclusion criteria: a) Adult patients (more than 18 years) with a confirmed diagnosis of aSAH b) less than 5 days of ictus c) Able to undergo non-invasive testing ONSD measurement and AP.
Exclusion criteria
Exclusion criteria: a) Pre-existing eye diseases or optic nerve pathology (e.g., optic neuritis, glaucoma). b) more than 5 days of ictus c) Requirement for immediate surgery or interventions that prevent non-invasive testing. d) Pregnancy. e) Significant comorbidities, such as terminal cancer, that would complicate the study s outcome measures
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Extended Glasgow outcome scale [GOSE]) at discharge from hospital and at 3 months post aSAHTimepoint: Extended Glasgow outcome scale [GOSE]) at discharge from hospital and at 3 months post aSAH | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Mortality within 30 days of aSAH. 2. Delayed cerebral ischemia or vasospasm as detected on imaging or clinical examination. 3. Influence of confounding variables (age, gender, grades of aSAH, comorbidities, timing of measurement, hydrocephalus, Vasospasm, DCI, infarct) on predictive accuracy of ONSD & Pupillometry. Timepoint: 30 days | — |
Countries
India
Contacts
Public ContactDR RICHA PARIHAR
ALL INDIA INSTITUE OF MEDICAL SCIENCES NEW DELHI
Outcome results
None listed