Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Cisatracurium Besylate 0.20 mg/kg: Cisatracurium besylate 0.2 mg/kg is administered as an intravenous bolus during induction of general anaesthesia to facilitate endotracheal intubatio
Sponsors
BJ Medical College Ahmedabad
Eligibility
Inclusion criteria
Inclusion criteria: Patients in ASA I and II Patients who have signed a Valid Informed written consent. Patients posted for elective surgery under general anesthesia requiring endotracheal intubation. Surgeries with estimated duration of 45 minutes to 3 hours.
Exclusion criteria
Exclusion criteria: Patient refusing for consent. Patients with known and anticipated difficult airway (MPC III or IV) Patients with history of Asthma. Patients on antihistamine and anticonvulsants. Patients with history suggestive of sleep apnea. . Patients with history of Gastro Esophageal Reflex Disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of intubating conditions after administration of two different doses of cisatracurium (0.15 mg/kg vs 0.20 mg/kg) for endotracheal intubationTimepoint: Assessed after 180 seconds of cisatracurium administration, at the time of intubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes included intraoperative hemodynamics (HR, SBP, DBP, MAP) at defined time points and perioperative/postoperative adverse effects (allergic reactions, bronchospasm, hypotension, prolonged muscle weakness, residual paralysis). Timepoint: before intubation, during laryngoscopy, 1,5,10, 20,30,40,50,60,90,120,180 minutes and postoperative 24 hr. | — |
Countries
India
Contacts
Public ContactDr Siddharth B Parmar
B. J. Medical College , Ahmedabad
Outcome results
None listed