Health Condition 1: J181- Lobar pneumonia, unspecified organism
Conditions
Interventions
Intervention1: Dexmedetomidine infusion: Midazolam bolus 0.1mg/kg will be given to both groups, dexmedetomidine infusion dose 0.25mcg/kg/hour and titrated in increments of 0.25mcg/kg/hour upto maximum
Sponsors
Pt. Bhagwat Dayal Sharma post graduate institute of medical sciences
Eligibility
Inclusion criteria
Inclusion criteria: Children aged 1 month to 14 years on invasive mechanical ventilation in paediatric ICU
Exclusion criteria
Exclusion criteria: 1.Children with catecholamine-resistant shock. 2. Children already receiving continuous sedative infusion prior to PICU admission. 3. Children with baseline bradycardia. 4. Children with known atrioventricular conduction abnormalities or heart block.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The percentage of time spent in target sedation range as PSCH sedation algorithm for mechanically ventilated children.Timepoint: To be assessed after seven days | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Duration of mechanical ventilation (onset of ventilation to successful extubation) 2.Length of PICU stay 3.Incidence of adverse effects Bradycardia, Hypotension, Respiratory depressionTimepoint: To be assessed for seven days | — |
Countries
India
Contacts
Public ContactDrPallavi Parihar
Pt. Bhagwat Dayal Sharma post graduate institute of medical sciences , Rohtak
Outcome results
None listed