Comparison of two methods of diagnosing early postoperative cognitive disorders in elderly patients undergoing surgery under anaesthesia.

Comparison of two methods Mini mental state examination (MMSE) vs Montreal cognitive assessment (MoCA) in diagnosing early postoperative cognitive disorders in elderly patients undergoing elective surgery under general anaesthesia. - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/100347

Enrollment

Registered

2026-01-05

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Comparison of Mini mental state examination vs Montreal cognitive assessment in diagnosing early postoperative cognitive disorders in elderly patients undergoing elective surgery under

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged more 60y scheduled for elective surgery under general anaesthesia will be recruited preoperatively.

Exclusion criteria

Exclusion criteria: Patients who declined participation or were unsuitable for neurocognitive assessment, Previously diagnosed cognitive impairment, Severe visual/auditory impairments, Multiple procedures requiring anaesthesia scheduled during follow up, Illiterate patients or inability to comprehend.

Design outcomes

Primary

Measure	Time frame
To compare cognitive assessment results of elderly patients on MMSE and MoCA in order to assess early postoperative cognitive disorder after undergoing elective surgery under general anaesthesia.Timepoint: The patients will be enrolled preoperatively. Patients more than 60 years undergoing elective surgery under general anaesthesia will be administered MMSE and MOCA concurrently a day prior to surgery. The tests will be re administered within 48 hours postoperatively. As our focus is on diagnosing early postoperative cognitive disorders so we will focus on assessing patients within 48 hours of surgery under anaesthesia.	—

Measure

Time frame

To compare cognitive assessment results of elderly patients on MMSE and MoCA in order to assess early postoperative cognitive disorder after undergoing elective surgery under general anaesthesia.Timepoint: The patients will be enrolled preoperatively. Patients more than 60 years undergoing elective surgery under general anaesthesia will be administered MMSE and MOCA concurrently a day prior to surgery. The tests will be re administered within 48 hours postoperatively. As our focus is on diagnosing early postoperative cognitive disorders so we will focus on assessing patients within 48 hours of surgery under anaesthesia.

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Secondary

Measure	Time frame
To evaluate the predictive accuracy of MMSE & MoCA scores in identifying patients at risk of developing POCDTimepoint: The patients will be enrolled preoperatively. Patients more than 60 years undergoing elective surgery under general anaesthesia will be administered MMSE & MOCA concurrently a day prior to surgery. The tests will be re administered within 48 hours postoperatively.Data will be compiled, compared & appropriate statistical test will be applied to analyse the results.We will focus on assessing the patient within 48 hours of surgery as we are diagnosing early postoperative cognitive disorders.;To assess the correlation among MMSE & MoCA in the perioperative setting for diagnosing cognitive impairment.Timepoint: The patients will be enrolled preoperatively. Patients more than 60 years undergoing elective surgery under general anaesthesia will be administered MMSE & MOCA concurrently a day prior to surgery. The tests will be re administered within 48 hours postoperatively.Data will be compiled, compared & appropriate statistical test will be applied to analyse the results.We will focus on assessing the patient within 48 hours of surgery as we are diagnosing early postoperative cognitive disorders.;To identify which cognitive domains (e.g., memory, attention, executive function) show the most significant decline postoperatively, & determine how well MMSE & MoCA capture these domain-specific impairment. Timepoint: The patients will be enrolled preoperatively. Patients more than 60 years undergoing elective surgery under general anaesthesia will be administered MMSE & MOCA concurrently a day prior to surgery. The tests will be re administered within 48 hours postoperatively.Data will be compiled, compared & appropriate statistical test will be applied to analyse the results.We will focus on assessing the patient within 48 hours of surgery as we are diagnosing early postoperative cognitive disorders.	—

Measure

Time frame

To evaluate the predictive accuracy of MMSE & MoCA scores in identifying patients at risk of developing POCDTimepoint: The patients will be enrolled preoperatively. Patients more than 60 years undergoing elective surgery under general anaesthesia will be administered MMSE & MOCA concurrently a day prior to surgery. The tests will be re administered within 48 hours postoperatively.Data will be compiled, compared & appropriate statistical test will be applied to analyse the results.We will focus on assessing the patient within 48 hours of surgery as we are diagnosing early postoperative cognitive disorders.;To assess the correlation among MMSE & MoCA in the perioperative setting for diagnosing cognitive impairment.Timepoint: The patients will be enrolled preoperatively. Patients more than 60 years undergoing elective surgery under general anaesthesia will be administered MMSE & MOCA concurrently a day prior to surgery. The tests will be re administered within 48 hours postoperatively.Data will be compiled, compared & appropriate statistical test will be applied to analyse the results.We will focus on assessing the patient within 48 hours of surgery as we are diagnosing early postoperative cognitive disorders.;To identify which cognitive domains (e.g., memory, attention, executive function) show the most significant decline postoperatively, & determine how well MMSE & MoCA capture these domain-specific impairment. Timepoint: The patients will be enrolled preoperatively. Patients more than 60 years undergoing elective surgery under general anaesthesia will be administered MMSE & MOCA concurrently a day prior to surgery. The tests will be re administered within 48 hours postoperatively.Data will be compiled, compared & appropriate statistical test will be applied to analyse the results.We will focus on assessing the patient within 48 hours of surgery as we are diagnosing early postoperative cognitive disorders.

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Countries

India

Contacts

Public ContactDR MEDHA MEHLA

Pt. B.D. Sharma PGIMS, Rohtak

dranjughai@gmail.com9416974794

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026