Health Condition 1: H160- Corneal ulcer
Conditions
Interventions
Intervention1: There will be two groups in the study. Group A will be treated with standard of care and Group B will be treated with Autologous eye drops in addition to standard of care: Group A wil
Sponsors
PGIMER Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: KOH stain positive corneal ulcers,Mild to moderate in severity will be included in the study
Exclusion criteria
Exclusion criteria: Bacterial and mixed corneal ulcers,Ulcers warranting immediate surgical intervention (impending perforation/ perforated ulcer)Endophthalmitis,Known allergy to study medications ,Previous keratoplasty in involved eye Unwilling or unable to participate or follow up,Pregnant or breast-feeding females,Clinical evidence of herpetic keratitis,Age less than 16 years,Hepatitis B, C, HIV and Syphilis patients will be excluded from the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to re-epithelisationTimepoint: Outcome will be assessed on day 3, 7, 14, 21, 30,60 and 90. | — |
Secondary
| Measure | Time frame |
|---|---|
| Best spectacle-corrected visual acuity at 3 months Infiltrate size or scar size Ulcer depth Time to ulcer healing No of eyes requiring surgical procedures cyanoacrylate glue adhesive or therapeutic penetrating keratoplasty or Amniotic Membrane Transplant. Timepoint: Patients will be assessed on day 0, 3, 7, 14, 21, 30,60 & 90. Outcome will be recorded at 3 months. | — |
Countries
India
Contacts
Public ContactDr Indu Bala
Advanced Eye Centre, Department Of Ophthalmology, PGIMER, Chandigarh
Outcome results
None listed