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Comparison of two doses of sugammadex for safe removal of the breathing tube after ENT surgeries.

Comparison of Efficacy of two different doses of sugammadex for Extubation in ENT surgeries - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/100274
Enrollment
140
Registered
2026-01-05
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H958- Other intraoperative and postprocedural complications and disorders of the ear and mastoid process, not elsewhere classified Health Condition 2: H758- Other specified disorders of middle ear and mastoid in diseases classified elsewhere

Interventions

Intervention1: Sugammadex: Patients in this group will recieve Sugammadex 2mg/kg intravenous bolus for reversal of neuromuscular blockade at the end of ENT surgry,after achieving at least two twitches

Sponsors

India educational trust department of Anesthesia Mahatma Gandhi medical college and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.patients who are willing to participate in this study by written and informed consent 2.patients of either sex having age 18-65 years 3.Patients of ASA grade 1 and 2 4.patients undergoing elective ENT surgeries under GA

Exclusion criteria

Exclusion criteria: 1.History of drug allergy 2.Chronic opioid users 3.History of neurological or psychiatric illness 4.Previous known neuromuscular disease 5.Pregnant and lactating females

Design outcomes

Primary

MeasureTime frame
Time (in seconds) from intravenous administration of Sugammadex to successful tracheal extubationTimepoint: Measured from administration of Sugammadex until extubation,up to 15 minutes post administration.

Secondary

MeasureTime frame
Heart rate(bpm),blood pressure(mm hg) changes following sugammadex administration.Timepoint: Baseline( before Sugammadex). 2,5,10,15 minutes after Sugammadex administration.

Countries

India

Contacts

Public ContactDrSuresh Kumar Bhargava

Mahatma Gandhi medical college and hospital

suresh3559@yahoo.com9829063830

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026