Study on patients of chronic pancreatitis who require surgery with a novel method additional to routine surgery, involving surgical removal of nerves carrying pain sensation from Pancreas, to see whether the procedure can be done with improvement in pain relief and quality of life of the patients.

Assessing the Feasibility and Acceptability of Additional Pancreatic Nerve Plexus Neurotomy for Pain Management in patients undergoing Surgery for Chronic Pancreatitis- A Non-Randomized Interventional (PILOT) Study - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/100246

Enrollment

Registered

2026-01-02

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K861- Other chronic pancreatitis

Interventions

Intervention1: ADDITIONAL THERAPEUTIC PANCREATIC NERVE PLEXUS NEUROTOMY: SURGICAL DIVISION OF PANCREATIC NERVE HEAD PLEXUS ADDITIONAL TO ROUTINE STANDARD SURGICAL PROCEDURE FOR CHRONIC PANCREATITIS- P

freed as well as is possible, from the posterior abdominal wall, with gauze. Extensive Kocherisation done to liberate the head of pancreas

Plexus Pancreaticus Capitalis-I visualised. SMA identified by its pulsation. Large fan-shaped bundle of nerve fibers visualized extending from the right celiac ganglion to the upper medial margin of t

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion Criteria- Patients undergoing Surgical Procedure for Chronic Pancreatitis and satisfying the following criteria- ADULT age-group i.e., 18-65 years. Duration of illness more than 2 years. IZBICKI Pain Score more than 50.

Exclusion criteria

Exclusion criteria: Exclusion Criteria- Individuals with Pseudocyst, Walled-Off Necrosis, Recent attack of Acute Pancreatitis (4 weeks), Obstructive Jaundice, Pancreatic Mass/Lesion (suspected malignancy) Patient with Psychiatric Illness Patients denying consent

Design outcomes

Primary

Measure	Time frame
To assess the feasibility of Therapeutic Pancreatic Nerve Plexus Neurotomy in addition to Surgery in patients with Chronic PancreatitisTimepoint: Baseline (at time of intervention)	—

Secondary

Measure	Time frame
To compare the effects of Therapeutic Pancreatic Nerve Plexus Neurotomy in addition to Surgery on reduction in Izbicki Pain Score & the Quality-of-Life in patients with Chronic Pancreatitis. To assess the complications related to the additional Therapeutic Pancreatic Nerve Plexus Neurotomy in further courseTimepoint: 3 months, 6 months	—

Countries

India

Contacts

Public ContactDR SOMNATH MUKHERJEE

JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH, PUDUCHERRY

debasismbbs@gmail.com8763124660

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026