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Comparison of duration of analgesia of dexamethasone and dexmedetomidine added to local anaesthetic for ultrasound guided infraclavicular nerve block in upper limb surgeries

The comparative study of effect of perineural dexamethasone to dexmedetomedine as adjuvants to bupivacaine in ultrasound guided infraclavicular block for upper limb surgeries - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/100216
Enrollment
60
Registered
2026-01-02
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: PCS-

Interventions

Intervention1: Bupivacaine: 0.5% Bupivacaine (25ml) Control Intervention1: Dexamethasone: 6mg Dexamethasone (1.5ml) in 0.5% Bupivacaine(25ml) Control Intervention2: Dexmedetomidine: 75mcg Dexmedetomid

Sponsors

Dr Pavan D
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Patients willing to provide informed written consent 2)ASA physical status grade II 3) Patients undergoing upper limb surgeries

Exclusion criteria

Exclusion criteria: 1)Local infection at the injection site 2)Coagulopathy or on anticoagulant therapy 3)Allergy to local anaesthetics 4)Chronic opioid use or chronic pain disorder 5)Psychiatric illness affecting pain perception or consent 6)Patient with heart block, those on beta blockers Patient with severe systemic disorders

Design outcomes

Primary

MeasureTime frame
To compare the duration of analgesia of dexamethasone to dexmedetomidine as adjuvant to bupivacaine in patients undergoing upper limb surgery under ultrasound-guided infraclavicular brachial plexus (USG-ICBP) block.Timepoint: 18 months—

Secondary

MeasureTime frame
1)To assess the time of onset. 2)To compare duration of action. 3) To assess hemodynamic parameters perioperatively. 4)To assess the time to first rescue analgesia (in minutes from completion of surgery). 5)To assess the incidence of adverse effects: if anyTimepoint: 18months—

Countries

India

Contacts

Public ContactDr Pavan D

Bangalore medical college and research institute

naaz.banu2010@gmail.com9986053038

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026