Health Condition 1: F20-F29- Schizophrenia, schizotypal, delusional, and other non-mood psychotic disorders
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
Government Medical College, Patiala
Eligibility
Inclusion criteria
Inclusion criteria: 1)Age between 18 to 65 years. 2)Diagnosed with a psychotic disorder (e.g., schizophrenia, schizoaffective disorder, delusional disorder) based on DSM-5 criteria. 3)On monotherapy or combination therapy with atypical antipsychotics for at least 4 weeks. 4)Willing to give informed consent and participate in the study.
Exclusion criteria
Exclusion criteria: 1)History of pituitary tumors, primary hypothyroidism (ruled out on the basis of T4 and TSH levels), and polycystic ovarian syndrome. 2)Concurrent use of medications known to elevate prolactin (e.g., metoclopramide, domperidone, verapamil, OCPs, opioids). 3)Pregnant or lactating females. 4)Patients with significant medical comorbidities (like CLD, CKD) that may interfere with hormonal regulation or lab testing. 5)Those unwilling or unable to give consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prevalence of hyperprolactinemia in patients of psychotic disorders treated with atypical antipsychoticsTimepoint: 1 year | — |
Secondary
| Measure | Time frame |
|---|---|
| Association between specific atypical antipsychotic agents & serum prolactin levelsTimepoint: 1 year;Clinical & demographic factors associated with hyperprolactinemiaTimepoint: 1 year | — |
Countries
India
Contacts
Public ContactDr Ishita
Government Medical College, Patiala
Outcome results
None listed