To compare the changes in thickness of gums after injection of liquid platelet rich fibrin or hyaluronic acid or microneedling procedure

Comparative evaluation of gingival thickness after microneedling, hyaluronic acid and injectable platelet-rich fibrin (I-PRF): a single-center, randomized, parallel-group clinical trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/100185

Enrollment

Registered

2026-01-02

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Microneedling: Microneedling using 30 gauge lancet needles in patients with thin gingival phenotype Intervention2: Injectable Hyaluronic acid: Hyaluronic acid gel of concentration 20mg/

Eligibility

Inclusion criteria

Inclusion criteria: 1 Adults 18 to 60 years. 2 Single site, thin gingival phenotype ,buccal GT less than or equal to 1.0 mm measured at baseline 3 Good general health, ASA I II. 4 Non-smoker or light smoker ,less than 5 cigarettes per day. 5 Signed informed consent.

Exclusion criteria

Exclusion criteria: 1 Systemic disease affecting healing (uncontrolled diabetes, immunosuppression). 2 Pregnancy or lactation. 3 Use of medications affecting healing like steroids, bisphosphonates 4 Allergies to HA or components used.

Design outcomes

Primary

Measure	Time frame
Change in Gingival thicknessTimepoint: Change in Gingival thickness at baseline and one month	—

Secondary

Measure	Time frame
NillTimepoint: Nill	—

Countries

India

Contacts

Public ContactDr Khushee Agrawal

Yogita Dental College and Hospital

mailprs999@gmail.com9886191999

Outcome results