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A Study to Evaluate the Relationship Between a Urinary Biomarker Synaptopodin and Kidney Function in Patients with Diabetic Kidney Disease

Correlation of urinary glomerular podocyte biomarker - Synaptopodin levels with estimated glomerular filtration rate in diabetic nephropathy : An Observational Cross-Sectional study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/01/100180
Enrollment
90
Registered
2026-01-02
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E112- Type 2 diabetes mellitus with kidney complications

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Dr Naveena D
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged more than thirty years and less than sixty years Patients diagnosed with diabetes mellitus based on fasting blood sugar greater than one hundred and twenty six milligrams per decilitre or random blood sugar greater than two hundred milligrams per decilitre or glycated hemoglobin greater than six point five percent Patients with estimated glomerular filtration rate less than sixty millilitres per minute per one point seven three square metres Patients with urine albumin to creatinine ratio greater than or equal to thirty milligrams per gram of creatinine

Exclusion criteria

Exclusion criteria: Patients with coexisting hypertension along with diabetes mellitus Patients aged less than thirty years and more than sixty years Patients with established renal disease other than diabetic nephropathy Patients with active urinary tract infection or systemic illnesses such as tuberculosis or human immunodeficiency virus infection Patients with established autoimmune diseases such as systemic lupus erythematosus or immunoglobulin A nephropathy Patients with tubular disorders including acute tubular necrosis and tubulointerstitial nephritis Patients with acute or chronic exposure to nephrotoxic agents or medications including non steroidal anti inflammatory drugs angiotensin converting enzyme inhibitors angiotensin receptor blockers finerenone certain antibiotics such as aminoglycosides or chronic heavy metal exposure Patients with acute stress conditions such as dehydration fever exercise or pregnancy Patients with obstructive uropathy including renal tumours or renal calculi

Design outcomes

Primary

MeasureTime frame
To assess the correlation between urinary synaptopodin levels and estimated glomerular filtration rate in patients with diabetic nephropathyTimepoint: baseline

Secondary

MeasureTime frame
NilTimepoint: nil

Countries

India

Contacts

Public ContactDr Naveena D

Vinayaka Missions Kirupanandha Variyar Medical College Hospitals

mooks.stanlean@gmail.com9842459677

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026