Health Condition 1: J22- Unspecified acute lower respiratory infection
Conditions
Interventions
Intervention1: Nebulised Salbutamol in Magnesium Sulfate Solution: Evaluates additive bronchodilator effect of inhaled magnesium sulfate when combined with salbutamol
Control Intervention1: Salbutamol
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: Children with 2 to 14 years of age with minimum weight of 10 kgs diagnosed with moderate to severe acute exacerbation of asthma according to woods-Downes score.
Exclusion criteria
Exclusion criteria: Abnormal airway development, congenital respiratory disease. Children with cardiac abnormality. Children with known history of liver or kidney disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Need for mechanical ventilationTimepoint: At 60 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| Respiratory rateTimepoint: Before therapy, at 20 minutes, at 40 minutes, at 60 minutes;Heart rateTimepoint: Before therapy, at 20 minutes, at 40 minutes, at 60 minutes;Use of accessory musclesTimepoint: Before therapy, at 20 minutes, at 40 minutes, at 60 minutes;Auscultatory findingsTimepoint: Before therapy, at 20 minutes, at 40 minutes, at 60 minutes;Any other drug requirement like steroidsTimepoint: Before therapy, at 20 minutes, at 40 minutes, at 60 minutes | — |
Countries
India
Contacts
Public ContactKritika Sharma
Pt. Bhagwat Dayal Sharma Institute of Health Sciences, Rohtak Haryana
Outcome results
None listed