Health Condition 1: F840- Autistic disorder
Conditions
Interventions
Intervention1: Intrathecal autologous BMMNC transplantation plus standard medical and rehabilitation therapy.: This randomized, controlled, single blind trial includes 50 children (ages 3 15) diagnose
Sponsors
NeuroGen Brain and Spine Institute
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who are diagnosed as Autism on the basis of DSM V criteria 2. Patients whose parents are willing to give an informed written consent 3. Patients whose parents agree to adhere to the protocol and are willing to come for mandatory follow up assessments at regular intervals.
Exclusion criteria
Exclusion criteria: 1.Patients with other co-morbid neurodevelopmental disorders like mental retardation or cerebral palsy. 2.Patients with present malignancies or history of malignancies 3.Patients with positive HIV, Hepatitis B, Hepatitis C or any other acute infections 4.Patients with severe anemia, bleeding tendency; with blood hemoglobin levels below 8 g/dl. 5.Patients with any bone marrow disorders. 6.Severe renal or liver dysfunction. 7.Uncontrolled seizures
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety of the interventionTimepoint: 1 month 3 months 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Efficacy of interventionTimepoint: 1 month 3 months 6 months | — |
Countries
India
Contacts
Public ContactDr Nandini Gokulchandran
NeuroGen Brain and Spine Institute
Outcome results
None listed