Effect of ozone therapy on pain swelling and mouth opening after tooth extraction

Influence of Ozone on reducing pain edema trismus after extraction A Randomized controlled trial - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2026/01/100025

Enrollment

Registered

2026-01-01

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Ozonised Water: Ozonized distilled water was prepared 10 minutes before the surgery using ozone generator coupled to the glass column Built in internal air pump with multiple tubes and

Eligibility

Inclusion criteria

Inclusion criteria: Healthy patients aged 20 to 40 years Both male and female participants Patients requiring simple dental extraction Patients willing to participate voluntarily and provide written informed consent Patients able to comply with postoperative follow up visits Day 2 Day 4 Day 7

Exclusion criteria

Exclusion criteria: Medically compromised patients wwith systemic diseases Pregnant and lactating women Patients on ACE inhibitors Immunocompromised patients Patients with acute local infection at the extraction site Patients with known allergy to NSAIDs or antibiotics Patients currently on long term steroid or immunosuppressive therapy Patients unwilling to participate or unable to attend follow up visits

Design outcomes

Primary

Measure	Time frame
Reduction in pain will be seen in theTimepoint: Day2 Day4 Day7 Postoperatively	—

Secondary

Measure	Time frame
Wound healing & changes in edema & trismus will be seen in theTimepoint: Day2 Day4 Day7 postoperatively	—

Countries

India

Contacts

Public ContactDr R N Balakrishna

Tagore dental college and hospital

balakrishdr8394@gmail.com919790304198

Outcome results