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A study comparing two methods of giving oxygen (High flow nasal cannula and facemask) to improve oxygen levels during Anaesthesia in Adult Patients Undergoing Emergency Abdominal surgery

comparison of preoxygenation using High flow nasal cannula(HFNC) with facemask during Rapid sequence Induction in Adults undergoing Major abdominal surgery An open label Randomised Controlled Trial study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/12/099977
Enrollment
40
Registered
2025-12-31
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z518- Encounter for other specified aftercare

Interventions

Intervention1: High flow nasal cannula preoxygenation: preoxygenation using high flow nasal cannula delivering heated and humidified one hundred percent oxygen at thirty litres per minute for three mi

Sponsors

Postgraduate Institute Of Medical Education and ResearchPGIMER Chandigarh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients aged eighteen years or above undergoing emergency major abdominal surgery requiring rapid sequence induction under general Anaesthesia and willing to provide written informed consent

Exclusion criteria

Exclusion criteria: patients aged less than eighteen years pregnant patients, body mass index more than thirty five kilogram per square metre need for non invasive ventilation severe hypoxemia at base lin facial or nasal trauma preventing use of high flow nasal cannula or facemask predicted difficult airway severe cardiorespiratory instability or inability to provide informed consent

Design outcomes

Primary

MeasureTime frame
Lowest oxygen saturation measured by pulse oximetry during the apnoeic period from induction of Anaesthesia until successful tracheal intubationTimepoint: From induction of Anaesthesia until successful tracheal intubation (single intraprocedural assessment)

Secondary

MeasureTime frame
Duration of safe apnoeaTimepoint: From induction of anaesthesia until spo2 falls below 90 percent assessed during induction & intubation (single peri-intubation assessment);Arterial blood gas parameters including partial pressure of oxygen and carbon dioxideTimepoint: baseline before induction and immediately after intubation;Incidence of desaturation episodes during rapid sequence inductionTimepoint: During induction of anaesthesia & upto 1 minute after tracheal intubation

Countries

India

Contacts

Public ContactDr Kamal Kajal

Postgraduate institute of Medical Education and Research Chandigarh

vermpnm@gmail.com8284088601

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026