EFFECT OF LASER ASSISTED ARTICAINE LOCAL ANESTHESIA IN SINGLE VISIT ROOT CANAL TREATMENT FOR MANDIBULAR MOLAR WITH SYMPTOMATIC IRREVERSIBLE PULPITIS A RANDOMISED CLINICAL TRIAL.

EFFECT OF LASER ASSISTED ARTICAINE LOCAL ANESTHESIA IN SINGLE-VISIT ROOT CANAL TREATMENT FOR MANDIBULAR MOLAR WITH SYMPTOMATIC IRREVERSIBLE PULPITIS: A RANDOMIZED CLINICAL TRIAL. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/099956

Enrollment

Registered

2025-12-29

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: 1.980 nm diode laser Irradiation 2.suppplemental anaesthsia with 4% articaine: group 14% articaine, followed by adjunctive 980 nm diode laser irradiation group 2 supplemen

Eligibility

Inclusion criteria

Inclusion criteria: 1 Patients with normal general health willing to participate in this study 2 Patients aged 18-45 yrs 3 Mandibular molars with symptoms of irreversible pulpitis 4 Case that is ideal to perform single visit root canal technique. 5 Moderate to severe pain 6 Lingering response to cold pulp sensibility test

Exclusion criteria

Exclusion criteria: 1 Patients with systemic diseases or condition that hindering single visit root canal treatment. 2 Pregnant patients or nursing mothers. 3 Allergic to local anaesthesia. 4 Presence of any periapical radiolucency on radiographs. 5 Pain symptoms not indicative of irreversible pulpitis or no pain

Design outcomes

Primary

Measure	Time frame
Comparison of intraoperative pain control between diode laser group and articaine injection group during single visit root canal treatment of mandibular molar with sympromatic irreversible pupitis.Timepoint: Comparison of intraoperative pain control between diode laser group and articaine injection group during single visit root canal treatment of mandibular molar with sympromatic irreversible pupitis. it does not include weeks or months as it is single visit RCT, the time line is mostly baseline and post operative	—

Measure

Time frame

Comparison of intraoperative pain control between diode laser group and articaine injection group during single visit root canal treatment of mandibular molar with sympromatic irreversible pupitis.Timepoint: Comparison of intraoperative pain control between diode laser group and articaine injection group during single visit root canal treatment of mandibular molar with sympromatic irreversible pupitis. it does not include weeks or months as it is single visit RCT, the time line is mostly baseline and post operative

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Secondary

Measure	Time frame
the intraoperative pain scores measured during the root canal procedure using the Visual Analog Scale (VAS) & the recording of physiological parameters such as pulse rate. These measures supplement the primary outcome of anesthetic success by assessing patient comfort & systemic response during treatment. The study compares the effectiveness of 980 nm diode laser adjunct anesthesia versus conventional anesthesia methods in reducing pain intensity & physiological stress during endodontic therapy for symptomatic irreversible pulpitis within around 3 months of time in the upcoming yearTimepoint: The secondary outcome (intraoperative pain & pulse rate) was recorded continuously during root canal treatment & immediately post-operatively, within 3 months of time period	—

Measure

Time frame

the intraoperative pain scores measured during the root canal procedure using the Visual Analog Scale (VAS) & the recording of physiological parameters such as pulse rate. These measures supplement the primary outcome of anesthetic success by assessing patient comfort & systemic response during treatment. The study compares the effectiveness of 980 nm diode laser adjunct anesthesia versus conventional anesthesia methods in reducing pain intensity & physiological stress during endodontic therapy for symptomatic irreversible pulpitis within around 3 months of time in the upcoming yearTimepoint: The secondary outcome (intraoperative pain & pulse rate) was recorded continuously during root canal treatment & immediately post-operatively, within 3 months of time period

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Countries

India

Contacts

Public ContactDR Dhanavel C

INDIRA GANDHI ISNTITUTE OF DENTAL SCIENCE

drdhanavelods@gmail.com9944717497

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026