Effect of turmeric mouthwash and chlorhexidine mouthwash on prevention of lung infection in patients on ventilators

Evaluation of the effect of curcumin and chlorhexidine mouthwash on oral biofilm colonization and progression of ventilator associated pneumonia in mechanically ventilated patient: A randomized clinical study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/099937

Enrollment

142

Registered

2025-12-29

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J22- Unspecified acute lower respiratory infection

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: No history of pneumonia at the time of admission or prior history of pulmonary disease No allergy to curcumin No covid 19 infection Patient willing to participate

Exclusion criteria

Exclusion criteria: Facial fractures Pneumonia at the time of admission Patients not willing to give consent Fever greater than 38.50 Covid 19 infection APACHE 2 score greater than 30 More than three attempts at intubation

Design outcomes

Primary

Measure	Time frame
ONSET AND PROGRESSION OF VENTILATOR ASSOCIATED PNEUMONIA IN MECHANICALLY VENTILATED PATIENTSTimepoint: the outcome will be assesed on day 0, day 3, day 8	—

Secondary

Measure	Time frame
Secondary Outcomes Plaque Index Measured at baseline, Day 4, and Day 8 Beck Oral Assessment Scale scores Measured at baseline, Day 4, and Day 8 Change in periodontal parameters Clinical attachment level and probing pocket depth Effect of periodontal status on progression of VAPTimepoint: the outcome will be assesed on day 0, day 4, day 8	—

Countries

India

Contacts

Public ContactDr Pavitra Rastogi

Faculty of Dental Sciences, King Georges Medical University

pavitrarastogi@kgmcindia.edu8787221239

Outcome results