Health Condition 1: H475- Disorders of other visual pathways
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Group one will include healthy individuals with no history of diabetes, ocular disease, neurological disorders, or any history of eye surgery or trauma. Group two will include individuals diagnosed with Type one or Type two diabetes mellitus without any clinical signs of diabetic retinopathy on dilated fundus examination. Group three will include individuals diagnosed with Type one or Type two diabetes mellitus who have non proliferative diabetic retinopathy.
Exclusion criteria
Exclusion criteria: Individuals with proliferative diabetic retinopathy. Individuals with neurological disorders that affect the visual pathway. Individuals with media opacities such as cataract or corneal opacity that interfere with visual evoked potential recording. Individuals taking medications that can alter visual evoked potential results. Individuals with systemic illnesses, other than diabetes in groups two and three, that can affect the visual pathway.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess P100 latency(ms) changes on pattern visual evoked potentials in diabetic patients and compare with healthy controls at baseline(single visit)Timepoint: Single time point at baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate P100 amplitude differences among groups at baseline To correlate P100 latency and amplitude with HBA1c measured within 3 months of assessment To correlate P100 abnormalities with duration of diabetesTimepoint: Single time point at baseline | — |
Countries
India
Contacts
Alluri Sita Ramaraju Academy of Medical Sciences