Health Condition 1: K00-K95- Diseases of the digestive system
Conditions
Interventions
Intervention1: Probiotic with Phototherapy: Probiotic continued with phototherapy till the serum bilirubin level fall below phototherapy cutoff according to AAP guidelines at 2 intervals or maximum fo
Sponsors
Pandit Bhagwat Dayal Sharma PGIMS Rohtak Haryana India
Eligibility
Inclusion criteria
Inclusion criteria: All neonates with gestational age more than 35 weeks to 41 +6weeks who will reach the threshold for photography according to AAP 2022 guidelines for neonatal hyperbilirubinemia.
Exclusion criteria
Exclusion criteria: Preterm neonates more than 35 weeks. Elevated direct bilirubin levels. Any clinical or laboratory evidence of infection, any gross congenital malformations, glucose 6-phosphate dehydrogenase deficiency, history of maternal phenobarbital intake. 4. Critically sick neonates undergoing mechanical ventilation or in shock or on vasopressor support. 5. Neonates with critical heart disease, critical renal system anomaly, critical respiratory or gastrointestinal tract disease. Neonates who previously received phototherapy. Serum bilirubin levels reached the standard for exchange blood transfusion. Refusal of consent by parents/guardian.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of decline in serum bilirubin levels. Days of phototherapy. Duration of hospital stay. 4.Side effects of probiotic. i.Loose stools ii.Rash iii.Feed intolerance Abdominal distention Rebound hyperbilirubinemia. Timepoint: Baseline At 12 hours,24 hours ,48 hours and 72 hours and thereafter as per standardized unit protocol | — |
Secondary
| Measure | Time frame |
|---|---|
| NilTimepoint: Nil | — |
Countries
India
Contacts
Public ContactDr Priya Mahajan
Pandit Bhagwat Dayal Sharma PGIMS ROHTAK
Outcome results
None listed