A study comparing steroid injection alone versus steroid with joint-lubricating injection for pain relief and better shoulder function in frozen shoulder

Effectiveness of ultrasound guided intra-articular injection of Methylprednisolone acetate with Hyaluronic acid compared with injection Methylprednisolone acetate for pain relief and functional improvement in patients with Adhesive capsulitis: A randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/099851

Enrollment

Registered

2025-12-26

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M750- Adhesive capsulitis of shoulder

Interventions

Intervention1: High molecular weight hyaluronic acid and Methylprednisolone acetate: Ultrasound guided intra-articular injection of Methylprednisolone acetate 80mg with high molecular weight Hyaluroni

Eligibility

Inclusion criteria

Inclusion criteria: Diagnosed case of adhesive capsulitis Stage 1 to 3 adhesive capsulitis Patients who are willing to comply with the study and follow up assessments

Exclusion criteria

Exclusion criteria: Patients with uncontrolled diabetes History of shoulder trauma/surgery History of injection in the shoulder joint in past three months Non-steroidal anti-inflammatory drugs intake in last seven days Autoimmune disorders Impaired cognition Any febrile or infectious disease (systemic & local)

Design outcomes

Primary

Measure	Time frame
Pain relief and functional improvement in patients with adhesive capsulitisTimepoint: Baseline, 1 week, 4 weeks, 12 weeks	—

Secondary

Measure	Time frame
Not applicableTimepoint: Not applicable	—

Countries

India

Contacts

Public ContactGOKUL MURALIDHARAN

Regional Institute of Medical Sciences, Imphal

bimoldr@yahoo.com7005291542

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026