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The effect of temperature of irrigation during root canal treatment on the pain of painful teeth with infection

The effect of cryotreated and preheated sodium hypochlorite irrigation on postoperative pain after endodontic treatment of teeth with symptomatic apical periodontitis: a randomised controlled trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/12/099829
Enrollment
69
Registered
2025-12-24
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K044- Acute apical periodontitis of pulpal origin

Interventions

Intervention1: Cryotreated group: In this group, 4 degrees Celsius of 3 percent sodium hypochlorite will be used for irrigation of the root canal system. Twenty milliliter of 3 percent sodium hypochlo

Sponsors

Nodal Officer MultiDisciplinary Research Unit Regional Institute of Medical Sciences Imphal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients 18 years old and above requiring root canal treatment in posterior teeth with symptomatic apical periodontitis, patients not having taken any analgesic within 12 hours before treatment, patients with pain score ranging from moderate to severe on a visual analogue scale of pain score 0 to 10.

Exclusion criteria

Exclusion criteria: Patients not willing to participate in the study, patients with systemic diseases, pregnant women, patients with more than one tooth requiring root canal treatment, teeth with abscess, teeth that have undergone root canal treatment, non-restorable teeth, teeth with root canal calcification, teeth with severe periodontal disease and teeth that cannot be isolated with a rubber dam.

Design outcomes

Primary

MeasureTime frame
Use of cryotreated sodium hypochlorite as an irrigant during root canal treatment may reduce the intensity of post-operative pain and also the need of analgesic compared to the use of sodium hypochlorite at room temperature and at heated temperature.Timepoint: 6 hours, 12 hours, 24 hours, 48 hours and 72 hours after treatment.

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactKangjam Gunadhar Singh

Dental College, Regional Institute of Medical Sciences, Imphal.

kangjamgunadharsingh@gmail.com9871578327

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026