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Diaphragmatic Stimulation for Diaphragmatic Dysfunction as a result of Mechanical Ventilation in critically ill mechanically ventilated patients

Transcutaneous Electrical Diaphragmatic Stimulation (TEDS) for Ventilator Induced Diaphragmatic Dysfunction (VIDD) in critically ill mechanically ventilated patients: A Non-Randomized Interventional Study - TEDVID

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/12/099805
Enrollment
58
Registered
2025-12-24
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Transcutaneous Electrical Diaphragmatic Stimulation: As part of the intervention, the Principal Investigator shall ascertain the position of the Diaphragm using a Sonosite M-Turbo Ultra
otherwise, a surrogate will be briefed regarding the same. The physiotherapists then applied TEDS as per the ICU Physiotherapy protocol. TEDS is routinely done for spinal cord injury as per a standard

Sponsors

Abhijith Sivasankar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age greater than 18 years 2. Ventilated for at least 72 hours with a further anticipated stay of 3 or more days in the unit. 3. Evidence of VIDD as defined by a DTF less than 30% and/or DE less than 15 mm measured by POCUS. 4. Consenting to participate in the study

Exclusion criteria

Exclusion criteria: 1. Known paralysis of the phrenic nerve 2. Known neurological conditions affecting the motor neuron or the muscle 3. Decision to withhold life-sustaining treatment 4. Patients with skin lesions, infections or strictures at point of interest 5. Patients on high dose vasopressor support 6. Severe COPD (FEV1 less than 30%) 7. Patients with implanted cardiac support systems (pacemaker, implanted defibrillator) 8. Conditions that limit diaphragm movement (e.g., high intra-abdominal pressure, ascites, pregnancy, obesity (BMI greater than 35) etc.

Design outcomes

Primary

MeasureTime frame
To ascertain the change in Diaphragmatic Thickness Fraction and Diaphragmatic Excursion pre and post application of TEDS in critically ill ventilated patients with Ventilator Induced Diaphragmatic Dysfunction.Timepoint: Days 1, 3 and 7 of Intervention and or at the time of Weaning.—

Secondary

MeasureTime frame
To analyze the following clinical outcomes: 1. Duration of Mechanical Ventilation. 2. ICU & Hospital Length of Stay. 3. Incidence of Weaning Failure. Timepoint: Duration of ICU & Hospital Stay—

Countries

India

Contacts

Public ContactDr Abhijith Sivasankar

St. Johns Medical College Hospital

bhuvana.k@stjohns.in09945693221

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026