Health Condition 1: G64- Other disorders of peripheral nervous system
Conditions
Interventions
Intervention1: Transcranial Magnetic Stimulation: Repetitive pulse mode, Frequency 10Hz, Pulse per train 50, Number of trains 15, Pulse duration 5seconds, Interpulse duration 30seconds, Test duration
Sponsors
Dr Rajeswari Aghoram
Eligibility
Inclusion criteria
Inclusion criteria: Type 2 diabetic patients with diabetic neuropathy as defined by toronto clinical neuropathy score more than 9 and resistant pain defined as visual analogue score in the last one week more than 4 while being on at least one pain relief medication.
Exclusion criteria
Exclusion criteria: a) Any active ulcer or inflammation b) Any other cause that can explain the pain like fractures c) Past history of seizure or epilepsy in self or family.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To estimate the change in Visual analogue score (VAS) Timepoint: It will be estimated following 5 sessions of Repetitive Transcranial Magnetic Stimulation and also at the end of 2 weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| To estimate the change in visual analogue score at the end of 5 sessions, and at the end of 1 month and 2 month Timepoint: Visual analogue score is estimated at end of 5 sessions, 1 month and 2 months;To evaluate safety and tolerability of repetitive transcranial magnetic stimulation in this patient populationTimepoint: It will be estimated at end of 1 month;To evaluate its effect on nerve conduction parameters, Patient global impression of change and DN4 scale.Timepoint: Effect on Nerve conduction parameters will be estimated at end of 2 weeks, Patient global impression of change at end of 1 month and DN4 scale at end of 5 sessions, 2 weeks, 1 month and 2 months | — |
Countries
India
Contacts
Public ContactDr Rajeswari Aghoram
Jawaharlal Institute of Postgraduate Medical Education and Research
Outcome results
None listed