To compare the incidence of sorethroat following administration of two drugs - Magnesium and Ketamine through breathing route after surgery

Comparison of Aerosolised Magnesium Sulphate and Ketamine in alleviating Postoperative Sore Throat after General Anaesthesia with Endotracheal Intubation: A Prospective Randomized Study - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/099797

Enrollment

Registered

2025-12-24

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: PCS-

Interventions

Intervention1: Ketamine nebulization with Ketamine sulphate: To observe the incidence of post operative sore throat, cough and hoarseness of voice Control Intervention1: Magnesium sulphate nebulizatio

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA 1,2 and 3 2.Age 20-60 years of either sex 3.All patients undergoing GA with endotracheal tube 4.Surgical duration- 3 hours

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
To compare the efficacy of ketamine nebulization and magnesium sulphate nebulization in decreasing the incidence of postoperative sore throat (POST) following general anaesthesia with endotracheal intubation.Timepoint: Baseline, immediately after surgery,2,4,12 and 24 hours after operation	—

Secondary

Measure	Time frame
To observe and compare the incidence of postoperative cough and hoarseness of voice in both groups.Timepoint: Baseline, 2, 4 and 12hrs following endotrachaeal intubation	—

Countries

India

Contacts

Public ContactR Arun Kumar

PSG Institute of Medical Sciences and Research

nithikshaa@gmail.com914224345818

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026